The fact that fluoxetine led ITV News reported the story more sensitively and accurately, acknowledging serotonin reuptake inhibition in patients show that antidepressants cause diabetes. Psychopharmacology Sugr, BBC News and.
Back to Diabetes. While the review itself was thorough, the individual studies that were included in the review were of varying quality. They also used different methods, which makes it difficult to combine their results. These would be required to prove direct cause and effect causality. The researchers report an overall association between antidepressant use and diabetes, but they acknowledge that the studies gave mixed results and do not prove that antidepressant use causes diabetes. Any association between antidepressant use and type 2 diabetes is likely to be extremely complex and involve multiple factors.
If you are currently taking antidepressants you should not suddenly stop taking them as this could lead to a worsening of your symptoms as well as side effects. Fluoxetine increases insulin action in obese non-diabetic and obese non-insulin-dependent diabetic individuals. It seemed that high dose of venlafaxine increased glucose uptake and glucose usage in the peripheral tissues [ 28 ]. The drug doses were chosen based on their efficacy as antidepressants in previous behavioral studies 20, Although there are no significant differences in efficacy between agomelatine and other second-generation antidepressants, agomelatine is better tolerated than paroxetine and venlafaxine in terms of overall side effect [ ]. Hsieh says that for many conditions, there are alternatives to beta-blockers that might be used instead for people with type 2 diabetes. Thus, treatment with antidepressant drugs may interfere with blood glucose levels of non-diabetic depressive patients as well as induce changes in blood glucose levels of depressive diabetic individuals. With respect to the metabolic effects of citalopram and escitalopram, the results were different.